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Biodegradable Hydrogels Based on Alginate for Control Drug Delivery Systems

Mohammad Sadeghi1 * , Fatemeh Shafiei1 , Esmat MohammadinAsab1 , Laleh Mansour1 and Mohammad Javad Khodabakhshi1

1 Department of Chemistry, Science Faculty, Islamic Azad University, Arak Branch, Arak, Iran

DOI: http://dx.doi.org/10.12944/CWE.9.1.16

In this work, synthesis and swelling behavior of a superabsorbent hydrogel based on alginate and polyacrylamide (PAAm) was investigated. the structure of the product was established using FTIR and SEM spectroscopies.The alginate-polyacrylamide hydrogel exhibited a pH-responsive swelling-deswelling behavior at pH’s 3 and 9. This on-off switching behavior provides the hydrogel with the potential to control delivery of bioactive agents.

Alginate; Acrylamide; Hydrogel; Ibuprofen; Drug Delivery

Copy the following to cite this article:

Sadeghi M, Shafiei F, Mohammadinasab E, Mansouri L, Khodabakhshi M. J. Biodegradable Hydrogels Based on Alginate for Control Drug Delivery Systems. Curr World Environ 2014;9(1) DOI:http://dx.doi.org/10.12944/CWE.9.1.16

Copy the following to cite this URL:

Sadeghi M, Shafiei F, Mohammadinasab E, Mansouri L, Khodabakhshi M. J. Biodegradable Hydrogels Based on Alginate for Control Drug Delivery Systems. Curr World Environ 2014;9(1). Available from: http://www.cwejournal.org/?p=5827

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